Investigator Profiles

A hub of all investigators with faculty positions at our department. Visit the profiles for research overviews, contact information, etc.

Quick Search: Clear · Anesthesia Center for Critical Care Research · Anesthesia Research Center · Beecher/Mallinckrodt Laboratories for Molecular Pharmacology Research · Cardiovascular Research Center (CVRC) · Center for Translational Pain Research · Clinical and Biochemical Pharmacology Laboratory · Medical Device Plug-and-Play Interoperability & Cybersecurity Program · Neuroscience Statistic Research Lab · Pulmonary Imaging and Bioengineering Laboratories · basic · translational · clinical · anesthesia · biomedical engineering · cardiovascular · critical care · education · neuroscience · opioid · pain · pharmacology · pulmonary · quality and safety · statistics

Elie Adam, Ph.D.

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neuroscience; bioengineering; pharmacology; mathematics; hibernation
Sherif Ahmed, Ph.D., Pharm.D.

basic, translational, neuroscience

adeno-associated virus vectors; bacteria; cns; gene therapy; immunotherapies; lentiviral vectors; luciferases firefly; nanobiotechnology; nanoconjugates; schwann cell tumors; schwannoma; sciatic nerve; spinal cord; transport vesicles
Shihab Ahmed, M.B.B.S., M.D.

Center for Translational Pain Research

baclofen; blood patch epidural; chronic pain; epilepsy complex partial; headache disorders; pain medicine; reflex sympathetic dystrophy; spinal puncture; vertigo
David Arney, PhD, MPH

Medical Device Plug-and-Play Interoperability & Cybersecurity Program
Aranya Bagchi, M.B.B.S.

Anesthesia Center for Critical Care Research · basic, translational, clinical, critical care, cardiovascular, iron homeostasis

acute lung injury; cardiopulmonary physiology; critical care; iron homeostasis; lipoproteins; plasma substitutes; sepsis; shock; systemic inflammation; toll-like receptors
Xiaodong Bao, M.D., Ph.D.

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anesthesiology; perioperative complications; postoperative pain
Riccardo Barbieri, Ph.D.

basic, translational, cardiovascular, neuroscience

action potentials; arrhythmia, sinus; autonomic nervous system; baroreflex; electrocardiography; heart rate; models, cardiovascular; nonlinear dynamics; signal processing, computer-assisted
Amit Bardia, MBBS

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cardiopulmonary bypass; echocardiography; extracorporeal membrane oxygenation; hypotension; propofol
Lorenzo Berra, M.D.

Anesthesia Center for Critical Care Research · basic, clinical, critical care

acute lung injury; acute respiratory distress syndrome; airway inflammation; critical care; mechanical ventilation; nitric oxide; pneumonia; ventilation; ventilator-associated pneumonia
Edward Bittner, M.D., Ph.D.

clinical, critical care

airway management; antiemetics; clinical quality; critical illness; education and training; haloperidol; intensive care units; intubation intratracheal; length of stay; medical education; ondansetron; outcomes research; postoperative nausea and vomiting; quality improvement; respiration artificial; surgical procedures elective; tracheobronchomegaly; tracheostomy
Donald Bloch, M.D.

Anesthesia Center for Critical Care Research · basic, translational

antigens, nuclear; autoantigens; bone morphogenetic protein receptors, type i; cytoplasmic granules; cytoplasmic structures; liver cirrhosis, biliary; nuclear proteins; rna processing, post-transcriptional; rna, messenger
Gary J. Brenner, M.D., Ph.D.

basic, translational, neuroscience, pain

aavs; caspase 1; hyperalgesia; injections epidural; luciferases firefly; neurilemmoma; neurofibromatoses; nociceptors; posterior horn cells; receptors n-methyl-d-aspartate; schwann cell tumors; schwann cells; sciatic nerve; spinal cord
Emery Brown, M.D., Ph.D.

Neuroscience Statistic Research Lab · clinical, translational, anesthesia, neuroscience

action potentials; algorithms; anesthesia; anesthesia delivery; anesthesia general; anesthesia processes; brain signaling in anesthesia; eeg; eeg monitoring; electroencephalography; hippocampus; models neurological; neurons; propofol; signal processing computer-assisted
Maurizio Cereda, MD

Anesthesia Center for Critical Care Research, and Pulmonary Imaging and Bioengineering Laboratories · translational, critical care, pulmonary, biomedical engineering

acute lung injury; ards; computed tomography; functional magnetic resonance imaging; lung imaging; lung physiology; mechanical ventilation; respiratory mechanics
Lucy Chen, M.D.

Center for Translational Pain Research · clinical, translational, pain

acupuncture; acupuncture therapy; analgesics; analgesics opioid; complementary integrative medicine; data collection; opioid induced hyperalgesia; pain management; pain threshold; pain tolerance
Mabel Chung, M.D., M.P.H.

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cardiac anesthesiology; days at home; outcomes research; patient-centered outcomes
Joseph Cotten, M.D., Ph.D.

Beecher/Mallinckrodt Laboratories for Molecular Pharmacology Research · basic, translational, pharmacology, anesthesia, neuroscience, pulmonary

adrenal cortex; adrenal cortex diseases; anesthetic mechanisms and pharmacology; anesthetics inhalation; cystic fibrosis transmembrane conductance regulator; doxapram; etomidate; hypnotics and sedatives; large-conductance calcium-activated potassium channels; potassium channel blockers; potassium channels tandem pore domain; regulation of breathing; respiratory physiology; respiratory system agents; triazines
Hassan S. Dashti, Ph.D., R.D.

translational, clinical, cardiovascular, critical care, quality and safety

circadian rhythms; clinical trials; electronic health records; genetic epidemiology; large biobanks; nutrition; parenteral nutrition; perioperative care; precision medicine; sleep; wearables
Hao Deng, MD, MPH, MBA, DrPH(c)

Anesthesia Research Center · clinical, statistics

big data; biostatistics; epidemiology; evidence-based medicine; meta-analysis as topic; randomized controlled trials as topic; statistical analysis
Rooma J Desai, Ph.D.

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etomidate; gaba agonists; hypnotics and sedatives; receptors, gaba-a; receptors, serotonin, 5-ht3; serotonin 5-ht3 receptor antagonists; shaw potassium channels
Weihua Ding, M.D.

Center for Translational Pain Research · basic, translational, neuroscience, pain

behavior animal; brain imaging; ca1 region hippocampal; chronic pain and neurological disorders; cognitive impairment; cortical dynamics; cortical seizures; cortical synchronization; gut microbiota; gut-brain axis; low back pain; mice; models anatomic; trigeminal nerve diseases; trigeminal neuralgia
Lena E Dohlman, M.D., M.P.H.

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anesthesiology; critical care; developing countries; disaster medicine; disasters; international agencies; obturator nerve; pharyngitis; philippines; traumatic amputation; voluntary workers; world health
Yuanlin Dong

Anesthesia Center for Critical Care Research · basic, clinical, anesthesia, neuroscience, neuroplasticity, perioperative neurocognitive disorder
Peter Dunn, M.D.

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adrenal gland diseases; adrenergic beta-antagonists; anesthesia, conduction; anesthesia, general; aortic aneurysm, abdominal; vascular surgical procedures
Huajun Feng, Ph.D.

Beecher/Mallinckrodt Laboratories for Molecular Pharmacology Research · basic, translational, pharmacology, anesthesia, neuroscience, critical care

epilepsy; etomidate; gabaa receptors; general anesthesia; ion channels; noradrenergic neurotransmission; seizures; serotonergic neurotransmission; sudden unexpected death in epilepsy; sudep
Paul G Firth, M.B.Ch.B.

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altitude; altitude sickness; anemia sickle cell; anesthesia; anesthesiology; foreign bodies; mountaineering; numismatics; uganda
Francisco J Flores, Ph.D.

Neuroscience Statistic Research Lab · basic, pharmacology, neuroscience, anesthesia, stimulation

analgesia; anesthesia general; arousal; cerebral cortex; consciousness; thalamo-cortical network; thalamus
Stuart Forman, M.D., Ph.D.

Beecher/Mallinckrodt Laboratories for Molecular Pharmacology Research · basic, translational, pharmacology, anesthesia, neuroscience

allosteric drug mechanisms; alphaxalone; anesthetic drug development; anesthetics; anesthetics general; anesthetics inhalation; anesthetics intravenous; etomidate; general anesthesia; glycine; ion channel function; ion channel gating; ligand-gated ion channels; propofol; receptors gaba-a; receptors nicotinic
Lei Gao, M.B.B.S.

translational, neuroscience, biomedical engineering

actigraphy; alzheimer's disease; circadian rhythm; cognition; computational neurosciences; delirium; electroencephalography; melatonin; neurotrauma; non-linear dynamics; sleep; traumatic brain injury
Timothy Gaulton

Anesthesia Center for Critical Care Research, Anesthesia Research Center, Pulmonary Imaging and Bioengineering Laboratories · translational, clinical, biomedical engineering, critical care, pulmonary, statistics
Julian Goldman, M.D., FASA

Medical Device Plug-and-Play Interoperability & Cybersecurity Program · clinical, biomedical engineering

biomedical technology; closed-loop control; cybersecurity; equipment safety; interoperability; medical device informatics; medical device standards; monitoring physiologic; pulse oximetry; regulatory science; smart and autonomous medical systems
Dusan Hanidziar, M.D.

basic, translational, pulmonary, critical care

ards; critical care; inflammation; oxygen; purines; sedation
Ion Hobai, M.D., Ph.D.

basic, cardiovascular, critical care

anabolic agents; atrioventricular block; calcium; calcium channels l-type; heart failure; heart muscle physiology; indigotindisulfonate sodium; intracellular calcium homeostasis; intraoperative complications; nickel; nitric oxide; sarcoplasmic reticulum calcium-transporting atpases; sepsis; sodium-calcium exchanger
Timothy T Houle, Ph.D.

Anesthesia Research Center · clinical, statistics, pain

anesthesiology; forecasting; migraine disorders; pain; statistical analysis; time-series analysis
Kun Hu

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Fumito Ichinose, M.D., Ph.D.

Anesthesia Center for Critical Care Research · basic, translational, cardiovascular, critical care, anesthesia, neuroscience, pharmacology

cardiopulmonary resuscitation; guanylate cyclase; heart arrest; hibernation physiology; hydrogen sulfide; nitric oxide; nitric oxide synthase type ii; nitric oxide synthase type iii; thiosulfates; vasodilation
Yumiko Ishizawa, M.D.

basic, anesthesia

anesthesia; anesthesia general; anesthetics inhalation; carotid body; general anesthesia; global warming; halothane; nonlinear dynamics; reticular formation; unconsciousness
Seun Johnson-Akeju, M.D.

Neuroanesthesia Laboratory · anesthesia, neuroscience, delirium

anesthesia general; postoperative cognitive dysfunction
Youssef Jounaidi, Ph.D.

Beecher/Mallinckrodt Laboratories for Molecular Pharmacology Research · basic, translational, pharmacology, anesthesia, neuroscience

cancer immunotherapy; gabaa receptors; immune cells programming; immunopathology; natural killer cells
Mihir M Kamdar, M.D.

clinical, pain

abdominal pain; analgesics; antigens, ly; autonomic nerve block; calciphylaxis; carcinoma, non-small-cell lung; cd4-positive t-lymphocytes; celiac plexus; conscious sedation; cytokines; delivery of health care, integrated; internal medicine; lymphocyte activation; mice, inbred mrl lpr; needles; pain, intractable; palliative care; patient care planning; terminal care; truth disclosure
Jacqueline Lane, Ph.D.

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atp-binding cassette transporters; clock proteins; dna, circular; european continental ancestry group; factor ix; factor xi deficiency; glucose intolerance; lipoproteins; polymorphism, single nucleotide; sleep stages
Feng Liang, Ph.D.

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alzheimer's disease
Guoping Li, Ph.D.

Anesthesia Research Center · translational, biomedical engineering, cardiovascular, neuroscience

extracellular vesicles; heart failure; ipsc-based disease modeling; neurodegenerative diseases; trna-derived small rnas (tdrs)
Haobo Li, Ph.D.

Anesthesia Research Center · basic, translational, cardiovascular, critical care, pharmacology, neuroscience

aging; alzheimer disease; cardiomyopathy hypertrophic; diabetes; exercise; heart failure
Peng Li, Ph.D.

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biomedical signal processing; cardiovascular function; circadian rhythms; cognitive aging; dementia; sleep
Marco Loggia, Ph.D.

Athinoula A. Martinos Center for Biomedical Imaging · clinical, pain, neuroscience, opioid

arterial spin labeling; autonomic nervous system; blood oxygen level dependent fmri; chronic back pain; fibromyalgia; fmri; galvanic skin response; hot temperature; hyperalgesia; mr-pet; neuroinflammation; pain; pain perception; pain threshold; pet imaging; pet-mri; positron emission tomography
Jianren Mao, M.D., Ph.D.

Center for Translational Pain Research · basic, clinical, translational, neuroscience, pain, opioid

acute pain; analgesics opioid; cannabinoid receptor modulators; cannabinoids; cellular mechanisms of neuropathic pain; chronic pain; drug tolerance; hyperalgesia; morphine; neuralgia; neuronal apoptosis; neuropathic pain; opioid tolerance; pain; receptors glucocorticoid; spinal cord
John Marota, M.D., Ph.D.

basic, clinical, neuroscience

blood volume; cerebrovascular circulation; cocaine; contrast media; milrinone; nicardipine; somatosensory cortex
Jeevendra Martyn, M.D.

Clinical and Biochemical Pharmacology Laboratory · basic, translational, clinical, anesthesia, critical care, neuroscience, pain, opioid, muscle wasting,innate immune responses

acute pain; anti-inflammatory agents; apoptosis; burns; chronic pain; critical illness; innate immunity; insulin signaling; macrophages; microglia; mitochondria; motor neuron disease; motor neurons; muscle protein breakdown; muscle skeletal; muscle weakness; myopathies; neuromuscular junction; neuromuscular nondepolarizing agents; pain medicine; receptors cholinergic; receptors opioid; sepsis
Eizo Marutani, M.D., M.E.

Anesthesia Center for Critical Care Research · basic, translational, critical care, anesthesia, neuroscience, pharmacology

brain injuries; brain ischemia; cryoprotective agents; hydrogen sulfide; neurons; receptors n-methyl-d-aspartate; sulfides; thiosulfates
Tina B. McKay, Ph.D.

basic, translational, neuroscience
Keith Miller, Ph.D.

Beecher/Mallinckrodt Laboratories for Molecular Pharmacology Research · basic, translational, pharmacology, anesthesia, neuroscience

alcohols; anesthetics, general; diazomethane; etomidate; photoaffinity labels; receptors, gaba-a; receptors, nicotinic; torpedo
Jeremi Mountjoy, M.D.

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Alexander Nagrebetsky, M.D., M.Sc.

Pulmonary Imaging and Bioengineering Laboratories, Anesthesia Research Center · clinical, database research, postoperative pulmonary complications, thoracic anesthesia, one lung ventilation, ventilator-induced lung injury, space medicine, periprocedural, emergency and critical care in microgravity/space missions

acute lung injury; anesthesia; critical care; space flight; thrombocytopenia
Akito Nakagawa, Ph.D.

Anesthesia Center for Critical Care Research · basic, translational, biochemistry, hemoglobin, red blood cells, sickle cell disease

carbon monoxide; heme; hemeproteins; hemoglobin; high throughput screening; nitric oxide; oxygen; red blood cells; sickle cell disease; small molecules
Karen Nanji, M.D., M.P.H.

clinical, quality and safety

adverse drug reaction reporting systems; adverse drug reactions; clinical decision support; clinical innovation; clinical quality improvement; covid-19; health informatics; healthcare quality improvement; medical error reduction; medical informatics applications; medical order entry systems; medication errors; patient safety; severe acute respiratory syndrome
Christa Nehs, Ph.D.

Neuroscience Statistic Research Lab · basic, neuroscience, anesthesia, sleep, metabolism, aging

basic systems neuroscience; brain aging; electrophysiology; energy metabolism; general anesthesia; optogenetics; sleep
Ronald Newbower, Ph.D.

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diagnosis, computer-assisted; indicator dilution techniques; interprofessional relations; medical laboratory science; monitoring, physiologic; technology, medical; therapy, computer-assisted
Janice C Palaganas, Ph.D.

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education, medical, undergraduate; inservice training; intensive care units; leadership; nurse administrators
Robert Peterfreund, M.D.

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anesthesia; anesthesia, intravenous; catheterization, central venous; drug delivery systems; infusions, intravenous; methylene blue
May Pian-Smith, M.D.

clinical, quality and safety, obstetric anesthesia, education, simulation, teamwork, communication

cardiomyopathies; communication barriers; healthcare delivery; hot flashes; medical simulation; obstetrical safety; obstetrical simulation training; patient care team; power (psychology); preeclampsia; professional autonomy; safety management
Jason Z Qu, M.D.

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colon; dietary proteins; insulin growth factor; insulin resistance; insulin-like growth factor i; intestine small; malnutrition; protein deficiency; thymoma; tumor necrosis factor
James Rhee, M.D., Ph.D.

Cardiovascular Research Center (CVRC) · basic, cardiovascular, neuroscience, proteomics, ischemia reperfusion injury, aging, exercise

fasting; gluconeogenesis; hepatocyte nuclear factor 4; lipoprotein metabolism; lipoproteins; ppgc-1alpha; receptors cytoplasmic and nuclear
Jesse D Roberts Jr., M.D. M.S.

Cardiovascular Research Center (CVRC) · basic, translational, pulmonary, lung injury, newborn critical care

bronchopulmonary dysplasia; cyclic gmp; cyclic gmp-dependent protein kinases; guanylate cyclase; muscle smooth; nitric oxide; nuclear localization signals; persistent fetal circulation syndrome; pulmonary alveoli; pulmonary artery; pulmonary vascular diseases; transforming growth factor beta; vascular
Julia M Rosenbloom, M.D.

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anesthetics; gender equity; opioid prescribing policies; racial disparities
Katarina Ruscic, M.D., Ph.D.

basic, clinical, translational, anesthesia, critical care, plastic surgery, lymphatics, lymphedema

critical care; endothelium lymphatic; lymphatic diseases; lymphatic pumping; lymphatic system; lymphatic vessels; lymphedema
A. Sassan Sabouri, M.D.

basic (gross human anatomy), clinical (regional anesthesia), pain (acute pain)

acute pain; anatomy; nerve block; ultrasound
Daniel Saddawi-Konefka, M.D., M.B.A.

education, critical care

feedback; gme; improvement; mentorship; motivation; professional development; self-regulation
Kyan Safavi, M.D., M.B.A.

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choice behavior; databases, factual; developing countries; hospitals; information dissemination; intensive care units; patient admission; patient preference; surgical wound infection
Roberta Santiago, M.D., Ph.D.

clinical, critical care
Richa Saxena, Ph.D.

basic, translational, genetics

circadian rhythms; clock proteins; diabetes mellitus type 2; genetic loci; genetic variation; genome-wide association study; polycystic ovary syndrome; polymorphism single nucleotide; preeclampsia; sleep
Kendrick Shaw, M.D., Ph.D.

anesthesia, biomedical engineering, critical care, neuroscience

biology; engineering; mathematics; students; teaching
Shiqian Shen, M.D.

Center for Translational Pain Research · basic, translational, neuroimmune interactions, disease modeling

arthritis infectious; chemotherapy induced neuropathic pain; chronic pain; chronic pain and neurological disorders; drug resistance bacterial; forkhead transcription factors; gut microbiota; lyme disease; metabolomics; metagenomics; oxaliplatin; t-lymphocytes regulatory
Nathaniel M Sims, M.D.

clinical, translational

catheterization central venous; catheters indwelling; equipment safety; infusion pumps; infusions intravenous; maintenance; methylene blue; pharmacokinetics; smart pump
Ken Solt, M.D.

basic, translational, anesthesia, neuroscience, pharmacology

anesthetic mechanisms and pharmacology; anesthetics general; anesthetics inhalation; anesthetics intravenous; arousal; basic systems neuroscience; consciousness; dopamine uptake inhibitors; dopaminergic neurons; sleep
Abraham Sonny, M.B.B.S.

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critical illness; frailty; heart failure after liver transplantation; innate immunity; liver transplantation; sepsis; ventricular function
Fangyun Tian, PhD

basic, clinical, anesthesia, neuroscience
Dana Turner, PhD

Anesthesia Research Center · clinical, statistics

headache; headache disorders; migraine; migraine disorders; pain measurement; statistical analysis
Susana Vacas, MD, PhD

Anesthesia Research Center · basic, translational, clinical, anesthesia, neuroscience, pharmacology
Jose Venegas, Ph.D.

Pulmonary Imaging and Bioengineering Laboratories · basic, translational, pulmonary, biomedical engineering

acute lung injury; airway liquid absorption; asthma; bronchoconstricted asthmatics; bronchoconstriction; copd; inhalation therapy; lung; positron-emission tomography; pulmonary circulation; pulmonary embolism; pulmonary fibrosis; pulmonary gas exchange; pulmonary ventilation; respiration; respiratory mechanics
Kathleen Vincent, PhD

basic, anesthesia, neuroscience

basic research; neural circuits; neuroscience; postoperative cognitive dysfunction
Brian Wainger, M.D., Ph.D.

basic, translational, neuroscience, pain

als; amyotrophic lateral sclerosis; autonomic nervous system; cervical vertebrae; chronic pain; cyclic amp; injections intra-articular; ion channels; methylprednisolone; motor neurons; muscle proteins; post-traumatic headache; rna transfer; spinal nerves; trigeminal nerve; tyr
Jingping Wang, M.D., Ph.D., FASA

Anesthesia Center for Critical Care Research · clinical anesthesia research, perioperative opioid sparing management

colon; cyclins; fatty acids; hyperbaric oxygenation; limb ischemia; microtubule-associated proteins; mitogen-activated protein kinases; perioperative care; reperfusion injury
Jeanine Wiener-Kronish, M.D.

basic, translational, clinical, critical care

acute lung injury; bacterial toxins; bronchoalveolar lavage fluid; cystic fibrosis; pneumonia bacterial; pseudomonas aeruginosa; pseudomonas infections; ventilator-associated pneumonia
Tilo Winkler, Ph.D.

Pulmonary Imaging and Bioengineering Laboratories · basic, translational, pulmonary, critical care, biomedical engineering

18f-fdg; acute respiratory distress syndrome; ards; asthma; bronchoconstriction; carbon monoxide; computational image analysis; computational modeling; computed tomography; copd; ct; embolism; hypertension; inflammation; lung injury; perfusion; pet; positron-emission tomography; pulmonary imaging; respiratory mechanics; vasoconstriction; ventilation
Zhongcong Xie, M.D., Ph.D.

basic, clinical, translational, anesthesia, neuroscience, neuroplasticity, perioperative neurocognitive disorder

alzheimer's disease; amyloid beta-peptides; amyloid beta-protein precursor; anesthesia; anesthetics inhalation; caspase 3; cognition disorders; delirium; geriatric anesthesia; isoflurane; methyl ethers; neuropathogenesis; postoperative cognitive dysfunction
Yi Xin, PhD

Anesthesia Center for Critical Care Research, and Pulmonary Imaging and Bioengineering Laboratories · translational, biomedical engineering, critical care, pulmonary

acute lung injury; computed tomography; lung ventilation; magnetic resonance imaging; perfusion imaging
Shingo Yasuhara, M.D., Ph.D.

Clinical and Biochemical Pharmacology Laboratory · basic, translational, clinical, anesthesia, critical care, neuroscience, pain, opioid

burns; carbolines; metabolic anomalies; microcirculation; microscopic imaging; muscle skeletal; muscular dystrophies; myopathies; phosphodiesterase 5 inhibitors
Zerong You, Ph.D.

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brain injuries; complement c4; dna viruses; penaeidae; viral structural proteins
Binglan Yu, Ph.D.

Anesthesia Center for Critical Care Research · basic, translational, critical care, pulmonary, cardiovascular, biomedical engineering

blood substitutes; blood transfusions; e-cigarettes and vaping; hemoglobins; nitric oxide; portable nitric oxide generator; pulmonary and systemic vasoconstriciton; therapeutic nitric oxide; transfusion safety
Yi Zhang, M.D., Ph.D.

Center for Translational Pain Research · clinical, translational, pain

analgesics; chronic pain; chronic pain conditions; novel agents for pain relief; quantitative sensory testing; therapeutic interventions
Yiying Zhang, M.D., Ph.D

basic, translational, anesthesia, neuroscience, gut brain axis, mitochondria

alzheimer disease; anesthesia; brain aging; brain development; gut microbiome; mitochondria; neurodegenerative disease; neutrophilic inflammation